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The postnatal period is a critical period for the maturation of the immune and central nervous systems because at birth, these systems are still immature [45]

3.3 Metabolic reprogramming in M2 macrophages Unlike M1 macrophages, M2 macrophages hold an intact TCA cycle and enhanced mitochondrial OXPHOS

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Enzymatic modification of kyn can result in the formation of kynurenic acid, which acts as a photosensitiser and produces reactive oxygen species (104)

10.3390/cells13050410

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