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The role of glutamine in cancer cell growth Rapidly proliferating cancer cells take up glutamine from plasma via various amino acid transporters, and then it is converted to glutamate in the mitochondria by the two forms of glutaminase: kidney-type glutaminase (GLS)1 and liver-type GLS2 8

McDiarmid SV, Anand R, Lindblad AS

G.SutherlandR

Supported by these findings, many therapeutical strategies focusing on GCase have been introduced in recent years

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DSIP is not approved by the FDA or EMA for any indication