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Anti-inflammatory Strategies that increase the intake of anti-inflammatory and antioxidant compounds seem to hold the most potential for helping to manage BD

doi: 10.1038/nrg1708

However, factors such as cigarette smoking, subclinical infections, environmental pollutants, occupational exposures, chronic microaspiration of gastric content, abnormal lung microbiota composition, and genetic predisposition may cause repeated AEC injury ( Complex bidirectional interactions between epithelial cells, mesenchymal cells, and ECM subsequently induce a series of cellular events, including fibroblasts differentiation into myofibroblasts, migration, proliferation, and activation of AECs and fibroblasts, inhibition of apoptosis, and persistent abnormal ECM secretion

doi: 10.1056/NEJMoa0909809

Finally, add the termination solution

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