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Beneficial effects are particularly noted in populations with baseline Zn deficiency, malabsorption, or chronic inflammation

At the juxtaparanodes, contactin-2 interacts with Caspr2, and this association is necessary for clustering of voltage-gated potassium channels

Hence, while the effects of novel inhibitors of methionine biosynthesis (sulfate reduction), or specific fungal methyltransferases, could be minimal in mammals, this could allow selective fungal inhibition

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