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Knockdown efficiency was confirmed by qPCR and Western blotting

In the US, the average intake of -tocopherol from food (including enriched and fortified sources) for adults (19 years of age) is 7.2 mg/day (25)

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References Alvarez MC, Albuquerque MLL, Neiva HP, Cid L, Rodrigues F, Teixeira DS, Matos R, Antunes R, Morales-Snchez V, Monteiro D

Indeed, recent work with transgenic mice suggests that folate deficiency may predispose heterozygotes for the CBS defect to basal hyperhomocysteinemia (Lentz et al, 2000)

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