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In contrast, the effect of ligand-bound PlzA on RpoS-dependent gene regulation was selective, affecting only 55 of 75 BosR/RpoS-repressed genes (Supplemental Table 8) and 16 of 90 BosR/RpoS-upregulated genes in DMCs (Supplemental Tables 5 and 7)
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Therefore, in this paper, we propose an in silico methodology using network pharmacology to identify specific proteins that could be involved with CBZ and VPA-induced oxidative stress in the case of epilepsy
Yi, J.B
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