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Vitamin b12 and long acting hydroxocobalamin has been reported too be required for normal blood formation and for treating anemias

GSH is one of the body's principal antioxidant defense molecules, playing a crucial role in the detoxification of cytotoxic compounds and reactive oxygen species.10 Intracellular GSH concentrations differ among tissues, typically ranging from 1 to 10 mM, with the highest levels observed in the liver.11 Experimental supplementation of GSH in animal models has been shown to reduce hepatocyte apoptosis, lower plasma AST and ALT activities, and protect against microvascular reperfusion injury.12 Melatonin (Mel) is a hormone primarily secreted by the pineal gland, but it is also synthesized in various tissues, including the ovaries, retina, lens, bone marrow, and gastrointestinal tract.13 In the retina and gastrointestinal system, it plays roles in visual adaptation and oxidative protection, respectively

S.MosovskyS.et al (2020)

doi: 10.1016/j.smrv.2021.101572

The Importance of Intracellular Glutathione Levels Maintaining adequate intracellular levels of glutathione is crucial for several reasons: Antioxidant Capacity Glutathione is one of the body's most potent antioxidants

Plant Cell Physiol 57:13641376 Destro T, Prasad D, Martignago D, Lliso Bernet I, Trentin AR, Renu IK, Ferretti M, Masi A (2011) Compensatory expression and substrate inducibility of -glutamyl transferase GGT2 isoform in Arabidopsis thaliana