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Kalluri, R., & Weinberg, R

This dualistic outcome likely stems from the distinct physiological roles of lactate and associated acidosis: elevated lactate itself may not impair muscle function and might even support performance, yet the concomitant severe intracellular acidosis (pH 6.56.2), especially in fast-twitch fibers, reduces calcium sensitivity and impairs myosin ATPase activity, ultimately inducing muscle fatigue

Among all the carotenoids, astaxanthin, a carotenoid belonging to the family of terpenes, has shown promising effects in the context of neurodegenerative disorders

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Due to its mild effect, it does not cause complications on the liver and kidneys
Volume loss is a different problem requiring different interventions
