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Available from: 10.1038/s41433-019-0750-2 [DOI] [PMC free article] [PubMed] [Google Scholar] Hesse, H

Basu, S

Antioxidant, anticonvulsant, and behavioral effe cts of KND proved to b e mor e prono unced than those of DSIP, suggesting the higher efficacy and therapeutic potential of KND and its derivatives

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Concurrently, it activates the HOXA9/MENIN pathway to upregulate the expression of key enzymes in the serine synthesis pathway and boost endogenous serine production, thereby remodeling serine metabolism and driving leukemogenesis (96)

Insights obtained from kinetic modeling
