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By modifying the structure of coumarin and introducing functional groups, researchers have synthesized more complex and diverse coumarin derivatives with more application value and more performance

Low temperature alters plant physiology leading to membrane damage, change in lipid composition, chlorosis and different enzyme activity leading to plant necrosis and even death too 2,3

This allows the reconstituted solution to remain stable for approximately 30 days when refrigerated

Tabe Y, Konopleva M, Kondo Y, Contractor R, Jin L, Ruvolo V, Tsutsumi-Ishii Y, Miyake K, Miyake N, Ohsaka A, Nagaoka I, Issa JP, Andreeff M

PMID: 12577686

Dose ladder: start at 5 units (0.5 mg) for Weeks 1 to 2, then step up to 8 units (0.8 mg) from Week 3 through Week 8