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A penile prosthesis may be appropriate in advanced cases.[12] Injections to plaques (scar tissue formed by the disease) with Verapamil may be effective in some patients

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Ni 2+ -loaded chelating Sepharose was used for the affinity purification of the target protein (Figure 2B, lanes 13 right )

Hyperglycemia can cause oxidative stress to produce many ROS, reduce the expression of anti-oxidant enzymes such as CuZnSOD ( SOD1 ) and MnSOD ( SOD 2), increase AGEs, activate protein kinase C (PKC) dependent ERK signaling pathway, and cause liver dysfunction

Batista, K