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Studies with fibroblast cell lines from Mrp1 knockout mice show a similar resistance pattern[31] [33], along with modest sensitization to taxanes and MX

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Peroxiporins such as AQP3/8 regulated H 2 O 2 membrane permeability and modulated EGFR-PI3K-AKT signaling, suggesting that AQP expression may help select patients for H 2 O 2 -focused therapies or CAP regimens with pronounced non-radical afterglow [266]

Madeira Rochas- Divulgaes Cientficas e Culturais (editor), Funchal, RAM, 344pp Singh R, Sharma B (2018) Chapter 9: Metal-based therapy in traditional and modern medicine systems