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Vitiligo, a chronic skin condition marked by the loss of pigment-producing cells called melanocytes, continues to challenge patients and clinicians alike

B12 deficiency upregulates lipogenesis in mature human WAT To validate the evidence of low B12 effect on lipogenesis in the Chub-S7 cells and primary Sc adipocytes, gene expression was further investigated in ScWAT and OmWAT derived from pregnant women with sufficient and deficient levels of B12

This selectivity is crucial because many methyltransferases play essential roles in neurotransmitter metabolism, gene expression, and protein function

VEGF-induced antidepressant effects involve modulation of norepinephrine and serotonin systems [296]

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these treatments are not universally available to all patients