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Our finding that there is only a small increase increase in covalent binding after a therapeutic dose, even with a four-fold increase in CYP P-450 activity supports this idea
FEBS J 274:21632180 Hicks LM, Cahoon RE, Bonner ER, Rivard RS, Sheffield J, Jez JM (2007) Thiol-based regulation of redox-active glutamate-cysteine ligase from Arabidopsis thaliana
These molecules help protect against oxidative stress
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The dotted line represents P = 0.05, log 2 (fold change) = 2.5
