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Classical treatment for vitamin B 12 deficiency is parenteral administration, usually intramuscular injection, to correct the deficiency and build up tissue storage

"Nicotinamide N-methyltransferase regulates hepatic nutrient metabolism through Sirt1 protein stabilization." Nature Medicine

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A daily multivitamin containing B 12 and folic acid is recommended for all people who could become pregnant, especially those with a vegan diet
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