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The representative protein sequences of CBS (YGR155W) and CGL (YAL012W) of Saccharomyces cerevisiae were retrieved from FungiDB

One of the biologically most active carotenoids against oxidative damage, lycopene, contains 11 conjugated double bonds and has been reported to have anticancer activities via regulation of oxidative enzymes such as cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), inhibitory effect on tumor growth and progression, triggering apoptosis, modulation of proteins involved in cell cycle regulation, reduction of the incidence of breast, liver, pancreatic and other cancers (Tang et al
Larsen, E

There is also some evidence that certain medications may be beneficial in repair of tendon, ligament, cartilage, and other collagen connective tissues

These findings comply with the current results, which confirmed that the FD at 50, 100 and 200 mg/kg doses exhibited neuroprotective effects, with no adverse reactions observed in the rat models

11 Both sulfasalazine and glutamate treatment reduced intracellular GSH levels in ANBL-6 cells (Figure 4a) and potentiated bortezomib-induced cytotoxicity in INA-6 and ANBL-6 cells (Figures 4be)
