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Induction of phosphoglycerate kinase 1 gene expression by hypoxia
doi: 10.1615/ForumImmunDisTher.2016017095 113 WangWFan YXW
A limitation of this study was the relatively low tumor uptake values seen compared to the uptake values observed in the study conducted by Mateusiak et al., describing the generation and validation of the uPAR15 sdAb ( 99m Tc]Tc(CO) 3 , and uPAR15-GEM-[ 99m Tc]Tc(CO) 3 -IRDye800CW in the same tumor model would be required to further assess the impact of the GEM-handle on the in vivo targeting of sdAb-based tracers
Molecular mechanisms of inflammation
Nausea occurs in up to 40% of subjects at standard doses, flushing in 2040%, and transient blood pressure elevation is documented
starvation, desiccation, extreme temperatures, and toxins)
