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[PubMed] [Google Scholar] 97.Weiden PJ, Du Y, Liu CC, Stanford AD

doi: 10.1111/j.1528-1167.2006.00830.x 48

This happens because certain MTHFR mutations (C667T and A129C) lower the amount of active folate being produced in the body, and the use of vitamin B12 requires the active form of folate

02 Where is glutathione formed

Since the mechanism of vitamin B12 availability in the diet is limited to animal products, and the mechanisms of its absorption are very complex, many different pathogenetic factors may underlie the deficiency