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Whereas, a large number of ROS including superoxide (O 2 ), hydroxyl radical (OH ), perhydroxyl radical (HO 2 ), and other types such as hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HOCl), and lipid peroxides (ROOH) [9], is generated as by-products of cellular aerobic metabolism upon different physiological and pathological changes, once exceeding the capacity of the cellular reductase mechanisms, which can result in direct or indirect functional damage to different molecules such as proteins, nucleic acids, and lipids, and eventually lead to cell death [10, 11]

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Therefore, we established the fixed-loss amount for site neutral payment rate cases as the corresponding IPPS fixed-loss amounts for FYs 2016 through 2023

Insufficient autophagy in idiopathic pulmonary fibrosis

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