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Hydropersulfides (RSSH) attenuate doxorubicin-induced cardiotoxicity while boosting its anticancer action

doi: 10.3748/wjg.v23.i29.5304

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Stored in the cytosol and mitochondria of liver cells, it acts as a potent antioxidant, neutralizing free radicals and reducing oxidative stress

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In our preclinical studies several animal models of stress were employed, such as the mild unpredictable stress for 7 days, the repeated restraint stress (2hrs per day x 4 days) and the maternal deprivation stress for 24hrs