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Prats-Galino, A., M

While IV detoxification is generally well-tolerated, some mild side effects may occur, including: These side effects of an IV detox are typically short-lived and resolve quickly

H., Patail, H., & Patail, H

There are still concerns about the safety of creatine supplementation, particularly in relation to kidney function, although many studies have not observed any significant changes in important renal markers, including mGFR, cystatin C, proteinuria, or albuminuria

This is supported by research showing that inhibiting mitochondrial fission through decreasing Drp1 leads to an increase in fatty acid content in lipid droplets and a decrease in fatty acid oxidation (65)