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Thus, genetic studies leave little doubt that NRF2 or KEAP1 may be mutated in human cancers and that the resultant increase in NRF2 activity can lead to resistance to classic cytotoxic chemotherapeutic agents

References 1 AhlborgB.AhlborgG

In one randomized study, patients receiving a ruscogenin-based formulation reported significant reductions in edema, bleeding episodes, and the need for analgesics compared to placebo groups

Fraternale, A., Paoletti, M

Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus

Belosic Halle Z, Vlainic J, Drmic D, Strinic D, Luetic K, Sucic M, et al
