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2023;324:H430H442

The activation of synaptic NMDAR promotes survival gene expression by activating Ca 2+ -dependent transcription factors such as cyclic-AMP response element binding protein (CREB) and suppresses caspases and apoptotic pathway such as Puma (pro-apoptotic Bcl2 homology domain 3 (BH3)-only member gene) - activated signaling cascade and transcription factor FOXO (forkhead box protein O) - induced pro-death gene expression (Hardingham and Bading 2010, Parsons and Raymond 2014)

Effect of isoniazid on vitamin D metabolism and hepatic monooxygenase activity

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Selected gRNAs ( Supplementary Table S1 ) were cloned into the pLentiCRISPRv2 vector and transformed into E

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