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doi: 10.1016/j.tifs.2022.02.004 109

(2022) 8(16):eabm8011

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Nonetheless, studying the molecular mechanism of the mitochondrial dysfunction could illuminate interacting networks that in turn may provide clues to the etiology of ME/CFS

The 1st glutathione-interaction site, also termed glutathione-scaffold site, is rather well defined and comprises several protein areas that altogether contribute to catalysis by interacting with the glutathione moiety of GSSR 7,8,13,14,15,35 , therefore explaining the specificity for the -glutamyl moiety 9,49,50