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S-amlodipine did not cause damage to hepatocytes in vitro , indicating that the liver dysfunction observed after S-amlodipine treatment was not due to the direct toxicity of S-amlodipine

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Research has shown GHK-Cu influences expression of over 4,000 human genes, stimulates collagen I, III and elastin synthesis, activates matrix metalloproteinases for extracellular matrix remodelling, supports angiogenesis through VEGF and FGF upregulation, and suppresses pro-inflammatory TNF- signalling