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Pineal Res Rev
The lux reaction requires reducing co-factors (NAD(P)H and FMNH 2 ), oxygen, and ATP, thus tightly coupling it to cellular metabolism 32
Explored in models of inflammation and oxidative injury where redox state can modulate signaling pathways and stress-response markers
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FAM-CAQK bound to proteins in the supernatant culture media of the U251 cells and to CSPGs complex purified from these cells (Fig
