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Theyre systemic signaling regulators, and their most important effects may have nothing to do with weight

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Therefore, viral vector-based models require a complex interplay between different types of immune cells, which may also best reflect observations made in human PD

These cumulative effects suggest Pb impairs GABAergic homeostasis by interfering with GABA synthesis, transport, and receptor function, contributing to excitatory/inhibitory imbalance and neurobehavioral deficits

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Additional information DISCLOSURE/CONFLICT OF INTEREST Michael Berk declares that over the past three years, he has received compensation from Stanley Medical Research Foundation, MBF, NHMRC, Beyond Blue, Geelong Medical Research Foundation, Bristol Myers Squibb, Eli Lilly, Glaxo SmithKline, Organon, Norvatis, Mayne Pharma and Servier