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Pharmacokinetics: Well absorbed orally

The erinacines studied had some similarities in their biological impacts

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Although A and APP levels were not affected in the early stages of hypercholesterolemia, the levels of presenilin 1 (PS1) that initiates A production were increased ( Hypercholesterolemia and Tau Pathology Tau is a microtubule-associated protein mainly expressed in neurons, and one of its main functions is to maintain the stability of axonal microtubules (Naseri et al., 2019)

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These conditions trigger systemic inflammation, vascular injury, and increased production of proteins involved in the clotting process, including von Willebrand factor, tissue factor, and fibrinogen