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Animals were housed at a controlled temperature (23 C) and controlled lightdark cycle (1212 h), with free access to water and food 16,17

Among the couples who consult for infertility treatment, approximately 15 % are diagnosed with unexplained infertility [103]

Figure 2 Interestingly, many of the initial studies elucidating NRF2-ARE-mediated cellular protection utilized tert -butyl hydroquinone (tBHQ), a synthetic antioxidant and inducer of the NRF2 pathway via its auto-oxidized, electrophilic form tert-butyl benzoquinone (tBQ) (Rushmore and Pickett, 1990

Cell Mol Biol Lett 27(1):136

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Stroke and the immune system: from pathophysiology to new therapeutic strategies