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A 2014 paper in the International Journal of Colorectal Disease reported a Phase 2 randomized controlled trial of ipamorelin for the management of postoperative ileus in bowel-resection patients, providing one of the few human-clinical-trial datasets for this class of molecule (PMID 25331030)

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doi: 10.1016/j.gene.2021.145996, PMID: [DOI] [PubMed] [Google Scholar] 45.Murphy EJ, Rezoagli E, Pogue R, Simonassi-Paiva B, Abidin IIZ, Fehrenbach GW, et al

ROS are also created as a result of phagocytosis by the RPE of the photoreceptors light absorbing photo-pigments contained in the outer segments (OS) 24