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It will be a major achievement to unravel those mechanisms and to steer these such that therapeutic targeting is most beneficial

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Anti-inflammatory mechanisms include modulation of inflammatory cytokines and reduction of nuclear factor-kappa B (NF-B) activity, a key inflammatory pathway

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Selection of candidate genes for mitochondrial translation inhibition The candidate list of genes mediating mitochondrial translation inhibition was selected based on gene and protein expression from Molenaars et al., available as supplemental data therein 16

Stone et al., 2019), cell aggregate-based models (Urich et al., 2013