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Emerging human data, including small pilot studies showing good tolerability (e.g., intravenous infusions up to 20 mg with no adverse effects) and subjective improvements in conditions like chronic knee pain, further support its promise

Tendon and Ligament Healing: May be used to support the healing of the connective tissue injuries, including cruciate ligament (ACL/CCL) tears, Achilles strain, and patellar instability

Tsimberidou AM, Thomas D, O'Brien S, Andreeff M , Kurzrock R, Keating M, Albitar M, Kantarjian H, Giles F

These motifs recur among top candidates and are reported in the interaction summaries to provide a concrete, residuespecific interpretation (Supplementary Table S2)

Wu Y, Zhao Y, Yang HZ, Wang YJ, Chen Y

Kupffer cells, the resident macrophages of the liver, and monocyte-derived macrophages have both been implicated as cells that both contribute to the injury and are critical for regeneration