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[DOI] [PubMed] [Google Scholar] 76.Meister A

They are: Not FDA-approved for wrinkle reduction Not supported by large clinical trials for cosmetic use Lacking standardized dosing and safety data The only injectable peptides currently approved by the FDA are GLP-1 medications (such as semaglutide and tirzepatide), and these are approved for diabetes management and weight loss, not cosmetic purposes

Olsen, D.L

Developmental time course of estradiol, testosterone, and dihydrotestosterone levels in discrete regions of male and female rat brain
Following each blood collection procedure, the catheter was flushed with a prepackaged saline syringe
Depending on the labeling instructions, intravenous formulations may have to be thrown out within 24 hours