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Disruption of carnitine homeostasis is also associated with pulmonary vascular endothelial dysfunction, and carnitine supplementation can alleviate this endothelial dysfunction by restoring nitric oxide signaling and reducing reactive oxygen species production [311]

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They also regulate the expression of antioxidant enzymes such as glutathione S-transferases [130], and stimulate the synthesis of hormones such as leptin, ghrelin, and GLP-1 [124, 127, 131]