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Classical Hodgkin's lymphoma (HL), which accounts for approximately 10% of all diagnosed lymphomas, is a B-cell lymphoid disease that is subdivided into classical HL and nodular lymphocyte-predominant HL [6]

In vivo animal experiments showed that daily administration of NNMTi for 28 days to dietinduced obese (DIO) mice significantly upregulated the expression of lipolysisrelated genes (such as ATGL and HSL) and downregulated lipogenesisrelated genes (such as FAS and ACC), indicating that NNMTi effectively promotes fat breakdown and inhibits fat synthesis

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