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These data re-enforce preclinical studies that suggest the antioxidant and anti-inflammatory activities of ergothioneine interfere with atherogenesis and protect vascular and microvascular endothelial cells from oxidative stress and hyperglycaemia (81)

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In addition, the discovery of the role of mitochondrial dynamics and autophagy in APAP-induced liver injury provides additional insight into the elaborate cell signaling mechanisms involved in the pathogenesis of this important clinical problem

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Part A, Clinical and Molecular Teratology , vol