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It supports the sustained biosynthesis of nonessential amino acids, proteins, nucleotides, and fatty acids, as well as the generation of the antioxidant NADPH [105]

Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1

Three inhibitors of mitochondrial fission have been identified as Mdivi 1, P110, and Dynasore [206-208] which play an ameliorative role against mitochondrial oxidative stress

[DOI] [PMC free article] [PubMed] [Google Scholar] Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP

Thus, there is much more to learn about the pathobiology of these syndromes

[DOI] [PubMed] [Google Scholar] 398