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This complex mechanism can take place during intra- and intercellular communication, the induction of the immune system and the response to external stimuli etc

oral regimens can be considered adjunctively

A common feature of many of these neurotoxic compounds, such as rotenone, paraquat, or MPTP, is the inhibition of mitochondrial complex I, followed by the overproduction of ROS, ATP exhaustion, and induction of a wide range of abnormalities that can elicit neuronal and astrocytic cell death [54]