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Unlike its cutaneous counterpart, oral melanoma lacks histopathological parameters that can reliably predict prognosis, for example, the Clark and Breslow classification and the ABCDEFG diagnostic scale that is normally used to diagnose nevi on the skin is not used for the pigmented lesions of the mouth mucosa

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Indeed, chromatin immunoprecipitation (ChIP)-qPCR experiments indicated that HLH-11 can directly bind to the promoters of lipl-3 and acs-2 (Supplementary Fig

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