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Autologous bone transplantation is currently considered the gold standard for bone defect restoration, distinguished by its osteogenesis, osteoconduction and osteoinduction properties

The thiol group is important this sulfur compound allows glutathione to donate electrons to neutralize reactive oxygen species ( ROS ) in the cell

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This suggests that stimulation of GSH and NADPH synthesis could be a potential intervention strategy in degenerative mouse retinas with RP

Oxidative stress occurs when theres an imbalance between the production of reactive oxygen species (ROS) and the bodys ability to neutralize them with antioxidants

Furthermore, mitochondrial ROS acts as signaling molecules mediating pro-inflammatory cytokines production, further reinforcing the connection between OxS and inflammation (47)