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MATERIALS AND METHODS Animal subjects All animal experiments were approved by the Animal Subjects Ethics Sub-Committee at The Hong Kong Polytechnic University (PolyU) and all experiments involving animals were performed under a valid license from the Department of Health of Hong Kong government in compliance with the Ordinance and The Code of Practice for Care and Use of Animals for Experimental Purposes of Hong Kong

B12 reduces these levels

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8,9 Additionally, the anti-CD38 antibody isatuximab was evaluated in the ICARIA-MM study, in which patients with multiple myeloma who had received multiple lines of therapy were randomized to receive (1) pomalidomide/dexamethasone/isatuximab or (2) pomalidomide/dexamethasone

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doi: 10.1016/j.jcmgh.2018.05.009 24 CirilloCSarnelliGEspositoGTurcoFSteardoLCuomoR