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Through these mechanisms, the combination of CPZ with rapamycin in vivo has been shown to delay remyelination, and prolong demyelination, a critical requirement for the testing of remyelination-based therapies (Sachs et al., 2014)

Global, regional, and national burden of Alzheimers disease and other dementias, 19902016: a systematic analysis for the global burden of disease study 2016

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Induced dementia was confirmed by behavioural tests, inflammatory cytokines and oxidative stress tests and histopathological signs of neurodegeneration, multifocal deposition of congo red stained amyloid beta plaques and the decreased optical density of HCN1 immunoreactivity

doi: 10.1016/S0149-7634(00)00027-0 146 PellegriniPContastaIDel BeatoTCicconeFBerghellaAM