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Thus, despite the demonstrated senolytic effects of BCL-2 family inhibitors, their clinical translation is limited due to potential side effects, off-target effects on platelets and poor central nervous system (CNS) penetrance

Peptides are also being investigated as potential biomarkers for chronic diseases, which could revolutionize early diagnosis and treatment

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These include microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), which are involved in macrophage polarization based on their ability to drive M1 or M2 polarization (235)

Over 212 peer-reviewed studies have examined this peptide most conducted in rodent models

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