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One study showed that both SVCT1 and SVCT2 are expressed by enterocytes, but their distribution in the plasma membrane is polarized, as SVCT1 is found in the apical side of cells (Figure 3.2) and SVCT2 is present in the basolateral membrane (Boyer et al., 3.3)

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Mitochondria-mediated metabolic abnormalities and cellular senescence As aging progresses, the mechanisms governing energy storage and expenditure required for cellular physiological homeostasis become increasingly dysregulated, often accompanied by significant metabolic abnormalities

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