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Finally, we highlight the unique ability of CnoX, apparently conserved during evolution, to cooperate with the GroEL/ES folding machinery

Blots images were analyzed with ImageJ gray value analysis tool

By reducing MDA levels and increasing SOD and GSH-Px activity, the combo therapy also strengthened antioxidant defense capacity, preventing ROS-induced lipid peroxidation, which is a significant factor in the progression of NAFLD from steatosis to NASH

However, one of the analyses suggested that cellular protection against -Syn derived toxicity could be instead related to the restoration of autophagic clearance [272]

In the right context, it can meaningfully support repair and recovery

These mechanisms are explored in depth in the following sections