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Nat Chem Biol 13:9198 Markovic M, Ben-Shabat S, Keinan S, Aponick A, Zimmermann EM, Dahan A (2019) Lipidic prodrug approach for improved oral drug delivery and therapy

In MS, GSH metabolism is impaired in regions of the CNS that have been demyelinated and correlates with mitochondrial dysfunction and axonal injury ( 2 Mechanisms of redox regulation in the CNS 2.1 GSH as an antioxidant in the brain The brain, being one of the most metabolically active organs in the body, requires a large share of oxygen relative to its mass

Kaur, K., Carrazzone, R

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Frontiers in Plant Science , 7

These include red blood cells, neurons, the renal medulla, skeletal muscle under low oxygen, the testes, the lens and cornea, and embryonic tissues