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The balance between utilizing glutathione's protective properties for healthy cells while overcoming its protective role in cancer cells remains a significant challenge in oncology

doi: 10.1016/j.freeradbiomed.2016.12.009 81 SharmaRSharmaADwivediSZimniakPAwasthiSAwasthiYC

Laboratory investigation

Homocysteine was first discovered by Vincent du Vigneaud, an American biochemist, during his research on the metabolic pathways of sulfur-containing amino acids

In brief, RNA was extracted from cells of the indicated genotype using the Qiagen RNAeasy RNA extraction kit (Qiagen, Manchester, UK) following the manufacturers instructions.mRNA (1 g) was retrotranscribed into cDNA using High Capacity RNA-to-cDNA kit (Life Technologies, Paisley, UK)

and Mieyal J.J