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In a clinical trial, participants with obesity (without diabetes) experienced an average weight loss of 20% with tirzepatide, compared to 13.7% with semaglutide after 72 weeks

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En cas de carence en B12 mais avec un apport suffisant en vitamine B9, il peut ne pas y avoir de mgaloblastose (car on contourne ainsi le pige des folates), ce qui complique son diagnostic