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Because the liver is one of the main sites for carnitine synthesis, liver disease can impair carnitine synthesis, which further aggravates the above-mentioned pathological processes and promotes disease progression

[DOI] [PubMed] [Google Scholar] 115.Barbuti PA

Psychiatry 127 ZhouL.YangY.MouL.XiaX.LiuM.XuL.et al (2025)

This was paralleled by increased expression of ROS-sensitive transcriptional regulators of insulin sensitivity and ROS defense capacity, peroxisome proliferator-activated receptor (PPAR) and PPAR coactivators PGC-1 and PGC-1 only in the absence of antioxidants