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The chaperone balance hypothesis: the importance of the extracellular to intracellular HSP70 ratio to inflammation-driven type 2 diabetes, the effect of exercise, and the implications for clinical management

Since cobalamin is a co-factor of methionine synthase, vitamin B 12 deficiency manifests in a decreased methylation of Hcy to Met, which leads to elevated Hcy

16 The impact of this suggests that patients receiving pegcetacoplan would be able to continue finding objects, recognizing faces, and reading finer print for a lengthened period of time

Med Hypotheses (2006) 66:4551

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This dual mechanism, weight-mediated and insulin-mediated aromatase reduction, may explain why some endometriosis patients see improvements that seem disproportionate to their weight loss alone